Below an overview of all news and events related to DeCOI
Die Genomforschung spielt in der modernen Gesundheitsforschung eine zentrale Rolle und trägt heute bereits zur besseren Versorgung von Patienten bei. Bei Krebs kann die Analyse des individuellen Tumorerbguts genetische Veränderungen aufspüren, um diese mit gezielten Therapeutika zu behandeln. Genomische Analysen werden zudem seit einiger Zeit vermehrt eingesetzt, um die genetischen Ursachen von seltenen Krankheiten zu entschlüsseln. Die sensiblen Genomdaten bestmöglich zu nutzen und sie Wissenschaftlern in Deutschland und darüber hinaus auch der internationalen wissenschaftlichen Gemeinschaft verfügbar zu machen, und dabei gleichzeitig die Persönlichkeitsrechte der Patienten zu wahren, ist das Ziel des neu etablierten Konsortiums „Deutsches Genom-Phänom Archiv”. Die DFG fördert diese neue Dateninfrastruktur-Initiative als Teil der Nationalen Dateninfrastruktur-Initiative (NFDI) für zunächst fünf Jahre.
EN-Genome research plays a central role in modern health research and is already contributing to better patient care. In the case of cancer, the analysis of the individual tumor genome can detect genetic changes in order to treat them with targeted therapeutics. Genomic analyses have also been increasingly used for some time to decipher the genetic causes of rare diseases. Making the best possible use of sensitive genome data and making them available to scientists in Germany and beyond to the international scientific community, while at the same time protecting the personal rights of patients, is the goal of the newly established consortium “German Genome Phenomenon Archive”. The DFG is funding this new data infrastructure initiative as part of the National Data Infrastructure Initiative (NFDI) for an initial period of five years.
SCOG Virtual Lecture Series ‘Recent Advances in Single-Cell Omics’: Presented by Joachim L. Schultze (DZNE Bonn)
The current pandemic crisis triggered by SARS-CoV-2 leads to very different disease courses of COVID-19 ranging from very mild to very severe with multi-organ failure. A significant number of patients with severe symptoms even succumb the infection. The host’s cellular reaction seems to be of utmost importance and responsible for this heterogenous response to the virus. Clearly, single cell omics can significantly contribute to our understanding of cellular reactions of infected cells and the response of the immune cells towards the infected cells. Over the last weeks, the German COVID-19 OMICS Initiative was established to coordinate NGS-based research efforts in COVID-19 research in Germany and together with colleagues world-wide. I will present initial results from single cell omics studies that are conducted on patient samples derived from COVID-19 patients within DeCOI.
DeCOI meeting and updates.
DeCOI meeting to discuss possible funding structures to apply for.
First DeCOI Science Webinar on the first DeCOI single cell study being written up and submitted with the Title:
“Suppressive myeloid cells are a hallmark of severe COVID-19“
presented by Birgit Sawitzki (Charite, Berlin), Emmanuel Saliba (HIRI, Würzburg), and Jonas Schulte-Schrepping (LIMES-Institute, Bonn)
Updates on DeCOI manuscripts and acknowledgement of DeCOI in scientific publications.
The DeCOI board structure was finalized along
Short Youtube Video by the German Ministery of Health about the visit at Radboud.
Professor Schultze presents DeCOI at Radboud UMC in Nijmegen to Ministers of Health Hugo de Jonge from the Netherlands and Jens Spahn from Germany. Based on existing collaborations between Radboud UMC (LifeTime, ImmunoSep, Human Functional Genomics Projekt (HFGP) and bilateral projects between Radboud and the University of Bonn) DeCOI can now quickly extend its collaborative efforts towards European partners.
DeCOI will also collaborate with the large studies on effect of the BCG vaccines on coronavirus in the elderly initiated by Professor Mihai Netea at Radboud UMC.
DeCOI discusses the next steps in building the network in the weekly Zoom telco.
DeCOI meets the German Biobank Node. Professor Schultze presents the concept of DeCOI to the members of the German Biobank Node at their weekly online meeting. The close collaboration between DeCOI and the German Biobanks is emphasized at the meeting. Both networks agree on intensifying the collabortations.
DeCOI applied for funding for two modules by the National COVID-19 Research Network.
The network now includes more than 60 research groups at 42 institutions in Germany including 13 university hospitals
DeCOI is featured in a newspaper article (Generalanzeiger)
COVID-19: DeCOI initiates a study and asks former COVID-19 patients to participate.
Link to the Press Release by the
GenomforscherInnen haben sich in der Deutschen Covid-19 OMICS-Initiative (DeCOI) zusammengeschlossen. „Um die Hochdurchsatzsequenzierung optimal zu unterstützen, haben DeCOI und GBN/GBA eine enge Zusammenarbeit vereinbart, um schnellstmöglich geeignete Bioproben ausfindig zu machen und für die Sequenzierung zur Verfügung zu stellen“, erklärt GBN-Leiter Michael Hummel.
DeCOI meets LifeTime. At the weekly Sunday meetings of the LifeTime COVID-19 Task Force meeting Professor Schultze presents the concept of DeCOI.
Press Release: The formation of the DeCOI is featured by numerous participating institutions of DeCOI.
Link to Press Releases at the following institutions
- University of Bonn
- Tweet of the University of Bonn
- Max-Delbrück Center
- TU Dresden
- Excellence Cluster in Chronic Inflammation
- University of Kiel
- University of Cologne
- Max-Planck Institute of Molecular Cell Biology and Genetics
- German Biobank Node
- ZB MED
- Medizin Aspekte
DeCOI discusses two modules to be submitted to the National COVID-19 Research Network at its weekly ZOOM telco.
DeCOI discusses major research areas to be included into the program of DeCOI.
DeCOI welcomes new members to the Initiative. Scientists from more than 12 institutions already joined the initiative. Members of the DFG-funded NGS competence centers report about their most recent efforts in ramping up sequencing capacities in the fight against COVID-19.
Members of the DFG-funded NGS competence centers meet members of the German Human Genome Phenome Archive (GHGA) consortium in a virtual meeting to discuss further aspects of joining forces in the fight against the pandemics. They officially form the Deutsche COVID-19 OMICS Initiative. The initiative is open to all scientists in Germany with expertise in OMICS research and interested in providing their expertise in the fight against the pandemics.
The NGS-CN members meet for the next virtual meeting to discuss next steps in shaping the program in the fight against the pandemics.
The members of the NGS-CN competence centers define concrete projects to address questions concerning the viral genome, the host genome and functional genomics projects.
Members of the NGS-CN competence network meet to further discuss to join their forces and to formulate defined projects via virtual telco meeting.
A first joined meeting between members of the German Human Genome-Phenome Archive (GHGA) and the DFG-funded NGS competence centers was organized to evaluate a joint program against SAR-CoV-2.
Members of the NGS-CN competence centers meet to discuss a joined program in OMICS-research in context of the pandemic crisis.